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Tuesday, October 25, 2011

Seborrheic dermatitis

Lipophilic yeasts from Malassezia genus has been implicated in the development of this disorder

  • Pityrosporum ovale
Often associated with acne rosacea


Rx

  •  reduce inflammation/Rx discomfort
    • 1% HC cream tds for face/axilla/groin
      • or Advantan or Elocon for first 5-7 days
  • remove scale
    • 3% sulfur + 3% salicylic acid in emulsifying ung or similar keratolytic
    • tar-based product
  • target Malassezia
    • Hyrdrozole cream (1% HC + 1% clotrimazole)
    • Nizoral cream (ketoconazole)
    • Selsun shampoo (for scalp and body)
For recalcitrant or severe disease
--> oral azole e.g. ketoconazole (daily for 1/52); fluconazole (weekly for 2/52)
--> isotretinoin




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