Dermatology
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Sunday, January 1, 2012
Re Systemic Cyclosporin & Side Effects
Only use in conjunction with a specialist experienced in its use
Potential side effects
Raised BP
Hepatic dysfunction
Renal dysfunction
Pre-Rx check
BP
FBC; LFTs; UCEs; eGFR; lipids
Pregnancy test
If BP raised, consider
Rx calcium-antagonist to prevent renal loss
Do Not Use if Pregnant or Planning Pregnancy
Systemic agents
Methotrexate
Acitretin (Neotigason)
Isotretinoin (RoAccutane)
Tetracyclines
Further more
Acitretin & Isotretinoin
No pregnancy within 2 years of Rx cessation
Re Systemic Methotrexate & Side Effects
Potential side effects
Hepatitis
Cytopenia
Teratogenesis
Pre-Rx check
LFTs; FBC; UCEs; eGFR
Pregnancy test
Re Systemic Prednisolone & Side-Effects
Short-term
Raised intra-occular pressure
Adrenal insufficiency
Long-term
As / short-term
Hypertension
Osteoporosis
Occular
Glaucoma
Cataracts
Endocrine
Diabetes
Electrolyte imbalance
Weight gain; tends to be trunk and face
Pre-Rx check
BP
Intraoccular pressure
LFTs; UCEs; eGFR; fasting lipids & BSL
Long-term Rx check
BP
Eyes - intraoccular pressure; cataracts
Bone density
UCEs; fasting lipids & BSL
Milia or Miliaria
Milia
Keratin-filled cysts
Miliaria
Blocked sweat ducts
Compression Bandages & Stockings for Wounds
Pressure
18-24 mmHg
Jobst stockings
Varicose veins
Ulcer prevention
Mild edema
25-35
Venosan stockings
Varicose veins (severe)
Post limb DVT
14-17
If discomfort an issue with higher pressure / patient compliance
Should be properly measured
Wound Dressings
Examples of Brand Dressings for Different Types of Wounds
Venous
Zinc oxide
FlexiDress
Steripaste
Xs bacterial burden / Excessive moisture
Calcium alginate with antiseptic component (e.g. weak povidine-iodine)
Algisite M
Kaltostat
Hypergranulation
Hypertonic saine
Mesalt
Curasalt
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