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Thursday, January 5, 2012

Tinea or Pityriasis?

Fungi <--> Tinea
But "tinea" generally reserved to describe circinate lesions => 'ring worm'
- in particular, those caused by a dermatophyte

So, tinea => dermatophyte
Generally followed by the region it affects e.g. tinea pedis (foot); tinea corporis (trunk) etc.


Candida albicans and Malassezia furfur
- are yeast-like and not dermatophytes

Candida --> candidiasis
Mallassezia furfur --> pityriasis versicolor (misnomer = tinea versicolor)


Important reason for understanding this

  • Tinea, including onychomycosis (nails)
    • responds to terbinafine (e.g. Lamisil) and griseofulvin (e.g. Grisovin)
      &
      responds to the "azoles"
  • Candidiasis and pityriasis versicolor
    • do not respond to terbinafine or griseofulvin
      but
      respond to the "azoles"

So 
  • Tinea                                      --> terbinafine or griseofulvin or an azole
  • Candidiasis                          --> an azole
  • Pityriasis versicolor             --> an azole

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